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Research Article
Lithology, Sulfide Mineralization, and Hydrothermal Alteration in an Emerging Birimian Gold District: Yas Permit, Boundiali Area, Bagoue Basin, West African Craton
Issue:
Volume 13, Issue 6, December 2025
Pages:
170-179
Received:
10 October 2025
Accepted:
21 October 2025
Published:
28 November 2025
Abstract: The Birimian greenstone belts of West Africa are globally recognized for hosting some of the most prolific orogenic gold deposits. In Côte d’Ivoire, the Bagoue Basin forms a major segment of the Boundiali Belt and represents one of the most promising yet underexplored gold provinces. This study focuses on the lithological, petrographic, and mineralogical characterization of the volcano-sedimentary formations within the YAS exploration permit, located in the Boundiali area. The research is based on a detailed analysis of diamond drill cores obtained from three mineralized targets (Targets 2, 3, and 10). The intercepted sequences are dominated by sedimentary units including sandstones, shales, and polymictic conglomerates, locally intruded by fine-grained mafic dykes. These rocks display intense and multiphase hydrothermal alteration, mainly silicification, chloritization, carbonation, and potassic alteration, which are closely associated with polymetallic sulfide mineralization composed of pyrite, pyrrhotite, arsenopyrite, and chalcopyrite. The occurrence of visible gold within Target 3 confirms the presence of a structurally controlled orogenic gold system, spatially related to NE-SW-trending shear zones. Collectively, these results demonstrate the strong influence of structural and hydrothermal processes in the metallogeny of the Bagoue Basin and emphasize the significant exploration potential of the YAS permit for future large-scale gold discoveries in northern Côte d’Ivoire.
Abstract: The Birimian greenstone belts of West Africa are globally recognized for hosting some of the most prolific orogenic gold deposits. In Côte d’Ivoire, the Bagoue Basin forms a major segment of the Boundiali Belt and represents one of the most promising yet underexplored gold provinces. This study focuses on the lithological, petrographic, and mineral...
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Research Article
Productivity Evaluation of Hormone-primed Maize Seedlings Exposed to Microgravity Environment Simulated with 2d Clinostat
Issue:
Volume 13, Issue 6, December 2025
Pages:
180-197
Received:
18 October 2025
Accepted:
31 October 2025
Published:
9 December 2025
Abstract: The biggest challenges in long space exploration has been sustainable supply of basic life support. Plants are reliable sources of sustenance and survival because of their ability to produce Oxygen, Water, and Food. This is much more important as it provides a more sustainable energy source during space travel. Unfortunately, microgravity which is a common phenomenon in space could be hindrance to plant growth and development. This study investigated response of plant growth promoters to enhance survival, yield and development of a Zea mays exposed to Microgravity simulated environment using 2D Clinostat. Plant growth stimulators that were used are Indole-3-Acetic Acid (IAA), Sodium Nitroprusside (SNP) and Thiourea (TU) at concentrations of 100 ppm and 500 ppm respectively. The Zea mays seeds were subjected to clinorotation at 0.5 rpm, and 2.5 rpm, and were observed for 120 hr. After 120hrs, the microgravity-exposed seedlings were acclimatized in experimental plants in a well-ventilated screen house for 5 days and thereafter transplanted on the field, where plant growth and yield responses were observed for 12 weeks. The study showed that addition of growth stimulators enhanced significant positive association between plant total dry weight and oxygen production efficiency. This study addresses Millennium Development Goal 1: Eradicate extreme poverty and hunger. This it does by providing information on the possible adoption of a combination of microgravity and growth stimulation as a measure for improvement of maize, as yield increase was more than 50% through the adoption of this technology. Conclusively, growth chemo-stimulation with IAA and SNP enhanced plant growth, development and high yield of maize exposed to simulated microgravity using 2D-Clinostat.
Abstract: The biggest challenges in long space exploration has been sustainable supply of basic life support. Plants are reliable sources of sustenance and survival because of their ability to produce Oxygen, Water, and Food. This is much more important as it provides a more sustainable energy source during space travel. Unfortunately, microgravity which is ...
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Research Article
Efficacy of Antifungal Medicines Against Clinical Isolates of Candida Species Responsible for Vaginal Candidiasis from Regional Referral Hospitals in Tanzania
Issue:
Volume 13, Issue 6, December 2025
Pages:
198-207
Received:
20 October 2025
Accepted:
29 October 2025
Published:
9 December 2025
Abstract: Vaginal candidiasis, caused by Candida species affects a significant proportion of women worldwide. Although different antifungal medicines are being used to treat the infection, the emergence of resistance against these medicines have been reported. This study assessed the efficacy of antifungal medicines which are recommended for treatment in the Tanzania Standard Treatment Guidelines against clinical isolates of Candida spp. Presumptive Isolates of Candida spp. collected from Regional Referral Hospitals (RRH) were transported to the Tanzania Medicine and Medical Devices Authority (TMDA) Microbiology laboratory for identification and confirmation by PCR. The confirmed isolates were used for susceptibility testing to establish the efficacy of antifungal medicines. Results indicate that Candida albicans (54%) was the most prevalent Candida spp. among isolates collected. Among the antifungal medicines tested, Miconazole showed the highest efficacy against 229 isolates of Candida spp. with 89.2% of the isolates being susceptible. This was followed by Clotrimazole, with 79.9% and Nystatin, 79.5% of isolates were susceptible, while Voriconazole showed moderate efficacy with 68.9%. Fluconazole demonstrated the lowest efficacy among the tested antifungals with 63.3%. Both Candida albicans and non-albicans Candida spp. displayed similar susceptibility patterns. Out of the 229 Candida spp. isolates tested, 4.4% were found to exhibit multidrug resistance. Findings from this study suggest that despite the observed resistance, the majority of antifungal medicines listed in the Standard Treatment Guidelines in Tanzania remain effective and are still considered reliable for treating vaginal candidiasis.
Abstract: Vaginal candidiasis, caused by Candida species affects a significant proportion of women worldwide. Although different antifungal medicines are being used to treat the infection, the emergence of resistance against these medicines have been reported. This study assessed the efficacy of antifungal medicines which are recommended for treatment in the...
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Research Article
Integrative Approaches in Traditional Chinese Medicine: Mechanistic Insights into Neural Repair and Osteoarticular Regeneration
Issue:
Volume 13, Issue 6, December 2025
Pages:
208-212
Received:
21 October 2025
Accepted:
12 November 2025
Published:
11 December 2025
DOI:
10.11648/j.ajls.20251306.14
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Abstract: Traditional Chinese Medicine (TCM) integrates multimodal interventions,such as acupuncture, manual therapy, and herbal medicine, to address complex disorders involving neural degeneration, skeletal injury, and musculoskeletal impairment. In clinical practice, Osteoarthritis (OA) is a long-term degenerative joint condition marked by the breakdown of articular cartilage, changes in subchondral bone, and ongoing pain with functional limitations,and peripheral nerve injury is a common medical problem that can be caused by sharp instruments, firearms, stretching or compression. it affects over one million people worldwide annually, making it a global clinical issue with a substantial socioeconomic cost. This study synthesizes evidence from three investigations: (1) Electroacupuncture (EA) at GB30/ST36 alleviates sciatic nerve injury by suppressing autophagy in rats; (2) Meridian-based manual therapy improves shoulder mobility and modulates serum inflammatory cytokines (e.g., IL-10, TGF-β, TNF-α) in frozen shoulder patients; (3) Huangqi Guizhi Wuwu Decoction (HGWD) promotes osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) via ESR1 upregulation. These findings highlight autophagy regulation, immunomodulation, and stem cell differentiation as key mechanistic pathways through which TCM modalities exert their reparative effects. Collectively, these findings bridge traditional TCM practices with modern molecular insights, emphasizing autophagy regulation, immune response modulation, and stem cell differentiation as convergent therapeutic pathways. These results advocate for TCM integration into evidence-based regenerative medicine. This integrative approach not only deepens the scientific understanding of TCM mechanisms but also supports its clinical application in managing complex musculoskeletal and neurological conditions, offering promising avenues for developing novel treatment strategies that combine traditional wisdom with contemporary biomedical research.
Abstract: Traditional Chinese Medicine (TCM) integrates multimodal interventions,such as acupuncture, manual therapy, and herbal medicine, to address complex disorders involving neural degeneration, skeletal injury, and musculoskeletal impairment. In clinical practice, Osteoarthritis (OA) is a long-term degenerative joint condition marked by the breakdown of...
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Research Article
Therapeutic Efficacy of an Herbal Remedy in the Treatment of Some Chronic Viral Infectious Diseases
Jiangnan Feng*
,
Zhenghua Ma,
Meiying Gao
Issue:
Volume 13, Issue 6, December 2025
Pages:
213-217
Received:
10 September 2025
Accepted:
25 October 2025
Published:
11 December 2025
DOI:
10.11648/j.ajls.20251306.15
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Abstract: Backgound: Currently, there are still no satisfactory treatment options available for viral infectious diseases. Recent reports suggest that Marecipe AV, a herbal remedy, has shown significant therapeutic benefits in managing viral infections, especially those that are life-threatening, in both humans and animals. Methods: This review was compiled by analyzing published studies and integrating unpublished clinical and experimental data on Marecipe AV therapies from the original authors. Results: In managing postherpetic neuralgia, most patients experienced complete pain relief within 5 days of treatment. About 20% required 20 days or more of oral Marecipe AV therapy for full pain resolution. Once relieved, the pain did not return in any treated cases. All 28 patients achieved clinical cure, with no treatment failures. In managing feline chronic gingivostomatitis, all cats (62/62) treated with Marecipe AV monotherapy achieved clinical cure, resulting in a 100% treatment response and clinical cure rate. High recurrence rates were observed, with an 83.33% recurrence rate at 3 months in treated cases. In the group receiving three retreatments with Marecipe AV, the recurrence rate at 3 months was 28.57%. In managing feline infectious peritonitis (FIP), all treated cats showed a rapid response and reversal of disease signs within 2 to 5 days. The treatment response rate was 100%, with a mortality rate of 0% in the treatment group and 100% in the control group. For treating iridovirus infection in largemouth bass, final mortality dropped from 34% in untreated controls to under 1% in the treated group. By Day 7 post-treatment, virological clearance was observed in all 30 randomly sampled specimens, along with restored feeding behavior. The results of Marecipe AV herbal medicine in preventing the porcine reproductive and respiratory syndrome virus in domestic pigs showed that the treated group had a morbidity rate of 0%, while the untreated group had a morbidity rate of 41%. Additionally, the untreated pigs had a mortality rate of 21%. Conclusion: Marecipe AV herbal therapeutics has demonstrated a rapid ability to alleviate clinical symptoms and achieve complete clinical recovery for many chronic viral infections in humans, animals, and aquaculture species.
Abstract: Backgound: Currently, there are still no satisfactory treatment options available for viral infectious diseases. Recent reports suggest that Marecipe AV, a herbal remedy, has shown significant therapeutic benefits in managing viral infections, especially those that are life-threatening, in both humans and animals. Methods: This review was compiled ...
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